I said a few days ago that I would deal with glycation, and how I changed my lifestyle when I realized how badly that could affect you.
Glycation
Glycation is a process in the body when sugars combine problematically with protein or fats in our cells to produce non-functional, or glycated, tissue. Once formed, this tissue is difficult to break down.
This tissue, furthermore, produces substances – appropriately called AGEs or Aged Glycation Endproducts – which make the glycation worse and worse. So, the more glycated tissue you have, the more is piled on.
The best example of glycated tissue – which we all know about – is: WRINKLED SKIN. It wrinkles because the process of glycation is just destroying the functionality of the skin.
Glycation Affects Important Organs
However, glycation does not only affect the skin. The wrinkling is actually taking place throughout the body.
The skin can put up with a bit of wrinkling; but if organs which need to be flexible – primarily the heart, kidneys, eyes, brain – get too wrinkly, we have problems. Glycation also affects the inside of blood vessels helping cause atherosclerosis.
Most heart attacks, I’ve heard it said, are because of glycated tissue in the left ventricle – the part of the heart which needs to be most flexible.
Glycation and Diabetes
Glycation and Diabetes
Diabetes and Glycation
The reason diabetics get problems with these very organs is that their high blood sugar level is causing glycation – the combination of sugar and protein to form non-functional (glycated) tissue – to happen in the body much more.
Next, I will cover what causes glycation; and what I did to reduce it to a minimum for me.
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4 responses so far ↓
1 TC // Aug 21, 2009 at 4:52 pm
Isn’t atherosclerosis caused by inflammation of the lining of the blood vessels? When micro-abscesses or other inflammatory processes occur plaque begins to form. It is basically vascular scar tissue laid down to attempt to heal the damaged vessel. Maybe glycation affects the flexibility of the vessels, but does it really affect plaque formation?
2 malc // Aug 21, 2009 at 5:05 pm
Hi there. Thanks for the comment.
As well as glycation affecting proteins it also affects fats. My understanding is that it is glycated LDL which is the ’scar tissue’ you refer too. LDL plugs the ‘cracks’ caused by inflammation. So glycation does accelerate plaque formation.
Eg see this link for a diagram of this process.
3 sharon from eye wrinkles // Sep 24, 2009 at 3:35 pm
Interesting article and looking forward to learning more on Glycation. So is gycated tissue the cause of cellulite?
sharon @ eye wrinkles´s last blog ..Fight Against Wrinkle Formation
4 malc // Sep 24, 2009 at 6:36 pm
Hi. Fat is the main cause of cellulite. But toxins also play an important role – and this is where glycation comes in. Glycated tissue is hard and inflexible – and glycation causes connective tissue to degrade and scar tissue to form. So it is to be avoided!
Best
Malc
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